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Thimerosal Content in Currently Manufactured U.S. Licensed Vaccines Vaccine Trade Name Manufacturer Thimerosal Concentration 1 Mercury Anthrax Anthrax vaccine Emergent BioDefense Operations Lansing Inc. 0 0 DTaP Tripedia 2 Sanofi Pasteur, Inc ≤ 0.00012% ≤ 0.3 µg/0.5 mL dose Infanrix GlaxoSmithKline Biologicals 0 0 Daptacel Sanofi Pasteur, Ltd 0 0 DTaP-HepB-IPV Pediarix GlaxoSmithKline Biologicals 0 0 DT No Trade Name Sanofi Pasteur, Inc < 0.00012% (single dose) < 0.3 µg/0.5mL dose Sanofi Pasteur, Ltd 3 0.01% 25 µg/0.5 mL dose Td No Trade Name MassBiologics ≤ 0.00012% ≤ 0.3 µg mercury/0.5 ml dose Decavac Sanofi Pasteur, Inc ≤ 0.00012% ≤ 0.3 µg mercury/0.5 ml dose No Trade Name Sanofi Pasteur, Ltd 0 0 Tdap Adacel Sanofi Pasteur, Ltd 0 0 Boostrix GlaxoSmithKline Biologicals 0 0 TT No Trade Name Sanofi Pasteur, Inc 0.01% 25 µg/0.5 mL dose Hib ActHIB/OmniHIB 4 Sanofi Pasteur, SA 0 0 ...

Guidelines for safe exposure to methylmercury are based on the analysis of unintended environmental exposures resulting in overt toxicity. Such guidelines have been developed by three federal agencies and the World Health Organization (WHO). The World Health Organization recommends a limit of 3.3 micrograms of methylmercury/ kilogram of body weight/ week (0.47 micrograms/ kg/ day). Three U.S. federal agencies have set lower guidelines for methylmercury exposure:     Environmental Protection Agency: 0.1 micrograms/ kg/ day     Agency for Toxic Substances Disease Registry: 0.3 micrograms/ kg/ day     Food and Drug Administration: 0.4 micrograms/ kg/ day Although these guidelines are each slightly different, but each leaves a large margin for safety, and exposure to amounts that exceed these guidelines does not mean that the developing infant is exposed to toxic levels of mercury. A concentration of 1:10,000     = 0.01% concentr...

When pregnant women eat foods or take medicines that contain mercury, the mercury can be transferred to the developing fetus through the placenta. Infants can be exposed to mercury through foods, including breast milk, or medicines. Developing fetuses and young children are believed to be more susceptible to mercury exposure than adults because mercury can interfere with the developing nervous system. Guidelines for safe exposure to methylmercury, based on the analysis of cases where people were accidentally exposed to toxic levels of mercury, have been developed by three federal agencies1. Although the three agencies’ guidelines are each slightly different, each leaves a large margin for safety, and exposure to amounts that exceed these guidelines does not mean that the individual has been exposed to toxic levels of mercury. Additionally, it should be noted that, some studies show that ethylmercury (the kind to which thimerosal is metabolized) may be less toxic than methylmercury (the...

Thimerosal is the preservative of choice for vaccine manufacturers. First introduced by Eli Lilly and Company in the late 1920s and early 1930s, the company began selling it as a preservative in vaccines in the 1940s. Thimerosal contains 49.6 percent mercury by weight and is metabolized or degraded into ethylmercury and thiosalicylate. Mercury, or more precisely, ethylmercury, is the principle agent that kills contaminants. Unfortunately, mercury also kills much more than that. The Department of Defense classifies mercury as a hazardous material that could cause death if swallowed, inhaled or absorbed through the skin. Studies indicate that mercury tends to accumulate in the brains of primates and other animals after they are injected with vaccines. Mercury poisoning has been linked to cardiovascular disease, autism, seizures, mental retardation, hyperactivity, dyslexia and many other nervous system conditions. That's why the FDA rigorously limits exposure to mercury in foods and d...

Thimerosal in Vaccines Questions and Answers Vaccines are safe? FDA's Center for Biologics Evaluation and Research is responsible for regulating vaccines in the U.S. Before new vaccines are licensed, they are tested extensively for safety in the laboratory, in animals, and in successive stages of human clinical trials called phases . When a new vaccine is first tested in humans, a sponsor (a vaccine manufacturer, academic investigator or other individual or organization) must first submit an Investigational New Drug Application to FDA. If data at any stage of clinical development raise significant concerns regarding the safety of the product, FDA may request additional information or may halt ongoing or planned studies. Phase 1 studies typically enroll less than 20 participants and are designed to look for very common adverse events. Phase 2 studies may include up to several hundred individuals and are designed to look at the overall safety profile of the vac...