Thimerosal and Expanded List of Vaccines

Thimerosal Content in Currently Manufactured U.S. Licensed Vaccines
Vaccine Trade Name Manufacturer Thimerosal Concentration1 Mercury
Anthrax Anthrax vaccine Emergent BioDefense Operations Lansing Inc. 0 0
DTaP Tripedia2 Sanofi Pasteur, Inc ≤ 0.00012% ≤ 0.3 µg/0.5 mL dose
Infanrix GlaxoSmithKline Biologicals 0 0
Daptacel Sanofi Pasteur, Ltd 0 0
DTaP-HepB-IPV Pediarix GlaxoSmithKline Biologicals 0 0
DT No Trade Name Sanofi Pasteur, Inc < 0.00012% (single dose) < 0.3 µg/0.5mL dose
Sanofi Pasteur, Ltd3 0.01% 25 µg/0.5 mL dose
Td No Trade Name MassBiologics ≤ 0.00012% ≤ 0.3 µg mercury/0.5 ml dose
Decavac Sanofi Pasteur, Inc ≤ 0.00012% ≤ 0.3 µg mercury/0.5 ml dose
No Trade Name Sanofi Pasteur, Ltd 0 0
Tdap Adacel Sanofi Pasteur, Ltd 0 0
Boostrix GlaxoSmithKline Biologicals 0 0
TT No Trade Name Sanofi Pasteur, Inc 0.01% 25 µg/0.5 mL dose
Hib ActHIB/OmniHIB4 Sanofi Pasteur, SA 0 0
HibTITER Wyeth Pharmaceuticals, Inc. 0 0
PedvaxHIB liquid Merck & Co, Inc 0 0
Hib/HepB COMVAX5 Merck & Co, Inc 0 0
Hepatitis B Engerix-B
Pediatric/adolescent
Adult
 GlaxoSmithKline Biologicals  
0
0
0
0
Recombivax HB
Pediatric/adolescent
Adult (adolescent)
Dialysis
 Merck & Co, Inc
0
0
0
0
0
0
Hepatitis A Havrix GlaxoSmithKline Biologicals 0 0
Vaqta Merck & Co, Inc 0 0
HepA/HepB Twinrix GlaxoSmithKline Biologicals < 0.0002% < 1 µg/1mL dose
IPV IPOL Sanofi Pasteur, SA 0 0
Poliovax Sanofi Pasteur, Ltd 0 0
Influenza Afluria CSL Limited 0 (single dose)
0.01% (multidose)		 0/0.5 mL (single dose)
24.5 µg/0.5 mL (multidose)
Fluzone6 Sanofi Pasteur, Inc 0.01% 25 µg/0.5 mL dose
Fluvirin Novartis Vaccines and Diagnostics Ltd 0.01% 25 µg/0.5 ml dose
Fluzone (no thimerosal) Sanofi Pasteur, Inc 0 0
Fluvirin (Preservative Free) Novartis Vaccines and Diagnostics Ltd < 0.0004% < 1 µg/0.5 mL dose
Fluarix GlaxoSmithKline Biologicals < 0.0004% < 1 µg/0.5 ml dose
FluLaval ID Biomedical Corporation of Quebec 0.01% 25 µg/0.5 ml dose
Influenza, live FluMist MedImmune Vaccines, Inc 0 0
Japanese Encephalitis7 JE-VAX Research Foundation for Microbial Diseases of Osaka University 0.007% 35 µg/1.0mL dose
17.5 µg/0.5 mL dose
MMR MMR-II Merck & Co, Inc 0 0
Meningococcal Menomune A, C, AC and A/C/Y/W-135 Sanofi Pasteur, Inc 0.01% (multidose)
0 (single dose)		 25 µg/0.5 dose
0
Menactra A, C, Y and W-135 Sanofi Pasteur, Inc 0 0
Pneumococcal Prevnar (Pneumo Conjugate) Wyeth Pharmaceuticals Inc 0 0
Pneumovax 23 Merck & Co, Inc 0 0
Rabies IMOVAX Sanofi Pasteur, SA 0 0
Rabavert Novartis Vaccines and Diagnostics 0 0
Smallpox (Vaccinia), Live ACAM2000 Acambis, Inc. 0 0
Typhoid Fever Typhim Vi Sanofi Pasteur, SA 0 0
Vivotif Berna Biotech, Ltd 0 0
Varicella Varivax Merck & Co, Inc 0 0
Yellow Fever Y-F-Vax Sanofi Pasteur, Inc 0 0
Table Footnotes
  1. Thimerosal is approximately 50% mercury (Hg) by weight. A 0.01% solution (1 part per 10,000) of thimerosal contains 50 µg of Hg per 1 ml dose or 25 µg of Hg per 0.5 ml dose.
  2. Sanofi Pasteur's Tripedia may be used to reconstitute ActHib to form TriHIBit. TriHIBit is indicated for use in children 15 to 18 months of age.
  3. This vaccine is not marketed in the US.
  4. OmniHIB is manufactured by Sanofi Pasteur but distributed by GlaxoSmithKline.
  5. COMVAX is not licensed for use under 6 weeks of age because of decreased response to the Hib component.
  6. Children under 3 years of age receive a half-dose of vaccine, i.e., 0.25 mL (12.5 µg mercury/dose.)
  7. JE-VAX is distributed by Aventis Pasteur. Children 1 to 3 years of age receive a half-dose of vaccine, i.e., 0.5 mL (17.5 µg mercury/dose).

Comments

  1. Online pharmacy31 March 2020 at 01:33

    Thanks for providing such a valuable information with us.this is a very useful post.i am very thankful for your this best article.

    ReplyDelete

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